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1

Mercury Induces Cell Cytotoxicity and Oxidative Stress and Increases β-Amyloid Secretion and Tau Phosphorylation in SHSY5Y Neuroblastoma Cells

G. Olivieri, Ch. Brack, F. Müller-Spahn, H. B. Stähelin, M. Herrmann, P. Renard, M. Brockhaus, C. Hock

Journal:

Journal of Neurochemistry

Year:

2000

Language:

english

File:

PDF, 129 KB

english, 2000

2

Alzheimer's disease, depression and normal ageing: merit of simple psychomotor and visuospatial tasks

Marc Hofman, Erich Seifritz, Kurt Kräuchi, Christoph Hock, Harald Hampel, Alexandra Neugebauer, Franz Müller-Spahn

Journal:

International Journal of Geriatric Psychiatry

Year:

2000

Language:

english

File:

PDF, 119 KB

english, 2000

3

Heroin-induced deoxygenation of cerebral hemoglobin: Monitoring by means of near-infrared spectroscopy

C. Hock, R. Störmer, K. Dürsteler, F. Müller-Spahn, D. Ladewig, R. Stohler

Journal:

Annals of Neurology

Year:

1999

Language:

english

File:

PDF, 386 KB

english, 1999

4

Increased levels of τ protein in cerebrospinal fluid of patients with alzheimer's disease—correlation with degree of cognitive impairment

Christoph Hock, Sidonie Golombowski, Werner Naser, Franz MüLler-Spahn

Journal:

Annals of Neurology

Year:

1995

Language:

english

File:

PDF, 251 KB

english, 1995

5

Cytosolic free [Ca2+] in mononuclear blood cells from demented patients and healthy controls

Brigitta Bondy, Ute Klages, Franz Müller-Spahn, Christoph Hock

Journal:

European Archives of Psychiatry and Clinical Neuroscience

Year:

1994

Language:

english

File:

PDF, 552 KB

english, 1994

6

Increased blood mercury levels in patients with Alzheimer's disease

C. Hock, G. Drasch, S. Golombowski, F. Müller-Spahn, B. Willershausen-Zönnchen, P. Schwarz, U. Hock, J. H. Growdon, R. M. Nitsch

Journal:

Journal of Neural Transmission

Year:

1998

Language:

english

File:

PDF, 261 KB

english, 1998

7

Age Dependency of Changes in Cerebral Hemoglobin Oxygenation During Brain Activation: A Near-Infrared Spectroscopy Study

Hock, Christoph, Müller-Spahn, Franz, Schuh-Hofer, Sigrid, Hofmann, Marc, Dirnagl, Ulrich, Villringer, Arno

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

1995

Language:

english

File:

PDF, 368 KB

english, 1995

8

Increased cerebrospinal fluid levels of neurotrophin 3 (NT-3) in elderly patients with major depression

Hock, C, Heese, K, Müller-Spahn, F, Huber, P, Riesen, W, Nitsch, R M, Otten, U

Journal:

Molecular Psychiatry

Year:

2000

Language:

english

File:

PDF, 124 KB

english, 2000

9

The PHA-induced calcium signal in lymphocytes is altered after blockade of K+-channels in Alzheimer's disease

Brigitta Bondy, Marc Hofmann, Franz Müller-Spahn, Martin Witzko, Christoph Hock

Journal:

Journal of Psychiatric Research

Year:

1996

Language:

english

File:

PDF, 685 KB

english, 1996

10

Decrease in parietal cerebral hemoglobin oxygenation during performance of a verbal fluency task in patients with Alzheimer's disease monitored by means of near-infrared spectroscopy (NIRS) — correlation with simultaneous rCBF-PET measurements

Christoph Hock, Kersten Villringer, Franz Müller-Spahn, Rüdiger Wenzel, Hauke Heekeren, Sigrid Schuh-Hofer, Marc Hofmann, Satoshi Minoshima, Markus Schwaiger, Ulrich Dirnagl, Arno Villringer

Journal:

Year:

1997

Language:

english

File:

PDF, 377 KB

english, 1997

11

Interactive computer-based cognitive training in patients with Alzheimer's disease

M. Hofmann, C. Hock, A. Kühler, F. Müller-Spahn

Journal:

Journal of Psychiatric Research

Year:

1996

Language:

english

File:

PDF, 574 KB

english, 1996

12

Cortisol impairs free recall of long-term declarative memory in healthy human subjects

Dominique J.-F. de Quervain, Benno Roozendaal, Franz Müller-Spahn, James L. McGaugh, Christoph Hock

Journal:

Psychoneuroendocrinology

Year:

2000

Language:

english

File:

PDF, 88 KB

english, 2000

13

Interactive computer-training as a therapeutic tool in Alzheimer’s disease

Marc Hofmann, Alexander Rösler, Wolfram Schwarz, Franz Müller-Spahn, Kurt Kräuchi, Christoph Hock, Erich Seifritz

Journal:

Comprehensive Psychiatry

Year:

2003

Language:

english

File:

PDF, 91 KB

english, 2003

14

Cortical alterations of angiotensin converting enzyme, angiotensin II and AT1 receptor in Alzheimer’s dementia

Egemen Savaskan, Christoph Hock, Gianfranco Olivieri, Sybille Bruttel, Carolyn Rosenberg, Christine Hulette, Franz Müller-Spahn

Journal:

Neurobiology of Aging

Year:

2001

Language:

english

File:

PDF, 423 KB

english, 2001

15

191 Muscarinic agonists effects on APP processing — A potential causal treatment strategy in Alzheimer's disease

C. Hock, F. Müller-Spahn, S. Golombowski, J.H. Growdon, R.M. Nitsch

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 143 KB

english, 1996

16

665 Increased levels of tau protein in cerebrospinal fluid of patients with Alzheimer's disease — Correlation with degree of cognitive impairment and dependence on ApoE4 allele frequency

S. Golombowski, F. Müller-Spahn, W. Naser, C. Hock

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 291 KB

english, 1996

17

Dependence of cerebrospinal fluid Tau protein levels on apolipoprotein E4 allele frequency in patients with Alzheimer's disease

Sidonie Golombowski, Franz Müller-Spahn, Helmut Romig, Klaus Mendla, Christoph Hock

Journal:

Neuroscience Letters

Year:

1997

Language:

english

File:

PDF, 90 KB

english, 1997

18

Interleukin-6 (IL-6) and soluble forms of IL-6 receptors are not altered in cerebrospinal fluid of Alzheimer's disease patients

Pia März, Klaus Heese, Christoph Hock, Sidonie Golombowski, Franz Müller-Spahn, Stefan Rose-John, Uwe Otten

Journal:

Neuroscience Letters

Year:

1997

Language:

english

File:

PDF, 199 KB

english, 1997

19

Decreased trkA neurotrophin receptor expression in the parietal cortex of patients with Alzheimer's disease

Christoph Hock, Klaus Heese, Franz Müller-Spahn, Christine Hulette, Carlyn Rosenberg, Uwe Otten

Journal:

Neuroscience Letters

Year:

1998

Language:

english

File:

PDF, 243 KB

english, 1998

20

Rapid cortical hemoglobin deoxygenation after heroin and methadone injection in humans: a preliminary report

Rudolf Stohler, Kenneth M. Dürsteler, Robert Störmer, Erich Seifritz, Irene Hug, Jeanette Sattler-Mayr, Franz Müller-Spahn, Dieter Ladewig, Christoph Hock

Journal:

Drug and Alcohol Dependence

Year:

1999

Language:

english

File:

PDF, 126 KB

english, 1999

21

365 Decreases in cerebral hemoglobin oxygenation during brain activation in patients with Alzheimer's disease monitored by means of near infrared spectroscopy (NIRS) — Correlation with simultaneous rCBF-PET measurements

C. Hock, F. Müller-Spahn, K. Villringer, H. Heekeren, S. Schuh-Hofer, S. Minoshima, R. Wenzel, M. Schwaiger, A. Viliringer

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 128 KB

english, 1996

22

678 Elevated soluble interleukin-6-receptor-indices in Alzheimer's disease

H. Hampel, H.U. Kötter, C. Schneidert, D.A. Körschenhausen, N. Müller, C. Hock, F. Müller-Spahn, H.-J. Möller

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 147 KB

english, 1996

23

S.28.05 The role of antidepressants in the treatment of dementia

F. Müller-Spahn, Ch. Hock

Journal:

European Neuropsychopharmacology

Year:

1997

Language:

english

File:

PDF, 198 KB

english, 1997

24

P.4.018 Measurement of potential biological markers in alzheimer's disease — cerebrospinal fluid levels of amyloid precursor protein and tau protein derivatives

C. Hock, S. Golombowski, M. Herrmann, R.M. Nitsch, A.M. Bush, F. Müller-Spahn

Journal:

European Neuropsychopharmacology

Year:

1997

Language:

english

File:

PDF, 139 KB

english, 1997

25

P-8-16 Altered response of alzheimer patients lymphocytes to the mitogen PHA after K+-channel blockade

B. Bondy, M. Ackenheil, M. Hofmann, F. Müller-Spahn, M. Witzko, C. Hock

Journal:

European Neuropsychopharmacology

Year:

1995

Language:

english

File:

PDF, 270 KB

english, 1995

26

Computer-based Cognitive Training in Alzheimer's Disease Patients

M. HOFMANN, C. HOCK, F. MÜLLER-SPAHN

Journal:

Annals of the New York Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 411 KB

english, 1996

27

Near Infrared Spectroscopy in the Diagnosis of Alzheimer's Disease

C. HOCK, K. VILLRINGER, F. MÜLLER-SPAHN, M. HOFMANN, S. SCHUH-HOFER, H. HEEKEREN, R. WENZEL, U. DIRNAGL, A. VILLRINGER

Journal:

Annals of the New York Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 468 KB

english, 1996

28

Risk factors and differential diagnosis of Alzheimer’s disease

F. Müller-Spahn, C. Hock

Journal:

European Archives of Psychiatry and Clinical Neuroscience

Year:

1999

Language:

english

File:

PDF, 41 KB

english, 1999

29

Regional cerebral blood flow changes in patients with Alzheimer disease during performance of a Stroop task

Villringer, K., Hock, Ch., Minoshima, S., Wenzel, R., Wolf, I., Ziegler, S., Kruschke, C., Müller-Spahn, F., Villringer, A., Schwaiger, M.

Journal:

Year:

1996

Language:

english

File:

PDF, 92 KB

english, 1996

30

Increased CSF levels of nerve growth factor in patients with Alzheimer's disease

Hock, C., Heese, K., Muller-Spahn, F., Huber, P., Riesen, W., Nitsch, R. M., Otten, U.

Journal:

Year:

2000

Language:

english

File:

PDF, 119 KB

english, 2000

31

Reduced β-Amyloid Response in Lymphocytes of Patients with Alzheimer's Disease

Bondy, Brigitta, Hofmann, M., Müller-Spahn, F., Witzko, M., Hock, Ch.

Journal:

Pharmacopsychiatry

Year:

1995

Language:

english

File:

PDF, 406 KB

english, 1995

32

Treatment with the selective muscarinic ml agonist talsaclidine decreases cerebrospinal fluid levels of Aβ 42 in patients with Alzheimer's disease

Hock, Christoph, Maddalena, Alessia, Raschig, Andreas, Müller-Spahn, Franz, Eschweiler, Gerhard, Huger, Klaus, Hewer, Isabella, Hampel, Harald, Müller-Thornsen, Thomas, Oertel, Wolfgang, Wienrich, Mar

Journal:

Year:

2003

Language:

english

File:

PDF, 708 KB

english, 2003

33

Evidence of Blood-Cerebrospinal Fluid-Barrier Impairment in a Subgroup of Patients with Dementia of the Alzheimer Type and Major Depression: A Possible Indicator for Immunoactivation

Hampel, H., Müller-Spahn, F., Berger, C., Haberl, A., Ackenheil, M., Hock, C.

Journal:

Dementia and Geriatric Cognitive Disorders

Year:

1995

File:

PDF, 1.30 MB

1995

34

Clinical Presentation of Depression in the Elderly

Müller-Spahn, F., Hock, C.

Journal:

Year:

2009

Language:

english

File:

PDF, 483 KB

english, 2009